Substrate specificity of the ileal and the hepatic Na+/bile acid cotransporters of the rabbit. II. A reliable 3D QSAR pharmacophore model for the ileal Na+/bile acid cotransporter
To design a reliable 3D QSAR model of the intestinal Na+/bile acid cotransporter, we have used a training set of 17 inhibitors of the rabbit ileal Na+/bile acid cotransporter. The IC50 values of the training set of compounds covered a range of four orders of magnitude for inhibition of [3H]cholyltau...
Guardat en:
| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
1999-12-01
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| Col·lecció: | Journal of Lipid Research |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S0022227520320903 |
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