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A small-molecule HSP90 inhibitor, NVP-HSP990, alleviates rotavirus infection

ABSTRACT Rotavirus (RV) infection remains a leading cause of hospitalization and mortality among infants and young children. Despite global implementation of RV vaccines, hundreds of thousands of infants and young children still succumb to this disease each year due to ineffective treatment. In this...

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Hoofdauteurs: Yi Cao, Qingmin Zhu, Xiaoping Wu, Zhunyi Xie, Chengying Yang, Yanyan Guo, Dongwei Meng, Xinyuan Zhou, Yuzhang Wu, Jintao Li, Haiyang He
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2026-01-01
Reeks:Journal of Virology
Onderwerpen:
diarrhea
MAPK signaling pathway
NVP-HSP990
rotavirus
tight junctions
Online toegang:https://journals.asm.org/doi/10.1128/jvi.01883-25
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