Upregulated Ca<sup>2+</sup> Release from the Endoplasmic Reticulum Leads to Impaired Presynaptic Function in Familial Alzheimer’s Disease
Neurotransmitter release from presynaptic terminals is primarily regulated by rapid Ca<sup>2+</sup> influx through membrane-resident voltage-gated Ca<sup>2+</sup> channels (VGCCs). Moreover, accumulating evidence indicates that the endoplasmic reticulum (ER) is extensively present in axonal terminal...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
MDPI AG
2022-07-01
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| Seria: | Cells |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.mdpi.com/2073-4409/11/14/2167 |
| Etykiety: |
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