Is Ecopipam an effective treatment for Tourette syndrome? A systematic review and meta-analysis with GRADE assessment

Abstract Background and aim Tourette syndrome is a neurodevelopmental disorder characterized by the presence of motor and vocal tics, typically emerging in childhood. Ecopipam is a selective antagonist of the D1 dopamine receptor that has been evaluated in several trials for treating Tourette syndro...

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Autores principales:	Mohamed Khalafalla Darwish, Mohamed Nasser, Hazem E. Mohammed, Mohamed E. Haseeb, Mohamed Salem Abdelqader, Mohamed Khamis Abdullah, Mohamed Awad E. Ahmed, Mostafa Meshref, Zeyad Bady
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	SpringerOpen 2026-01-01
Colección:	The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Materias:	Tourette syndrome Ecopipam Yale Global Tic Severity Scale Meta-analysis
Acceso en línea:	https://doi.org/10.1186/s41983-025-01064-2
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