Peroxisome Proliferator-Activated Receptor Family of Lipid-Activated Nuclear Receptors Alpha Silencing Promotes Oxidative Stress and Hypertrophic Phenotype in Rat Cardiac Cells

The peroxisome proliferator-activated receptor family of lipid-activated nuclear receptors (PPARs) plays a critical role in the regulation of cellular lipid metabolism. In cardiac muscle, PPARα is highly expressed and regulates genes involved in fatty acid oxidation, but its activity is downregulate...

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Hauptverfasser:	Marzia Bianchi, Nadia Panera, Sara Petrillo, Nicolò Cicolani, Cristiano De Stefanis, Marco Scarsella, Domenico Ciavardelli, Fiorella Piemonte, Anna Alisi, Anna Pastore
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-08-01
Schriftenreihe:	Antioxidants
Schlagworte:	PPARα ROS Ebselen cardiac hypertrophy
Online-Zugang:	https://www.mdpi.com/2076-3921/14/9/1059
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