Adenosine Signaling as a Central Integrative Network in Cellular Stress Responses and a Therapeutically Actionable Target in Human Disease

Adenosine has emerged as a central metabolic signal linking cellular stress to systemic physiological adaptation. Under conditions such as hypoxia, ischemia, inflammation, and tissue injury, extracellular adenosine triphosphate (eATP) released from stressed cells is sequentially metabolized by the e...

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Autors principals:	Shakta Mani Satyam, Mohamed El-Tanani, Wasim Iyad Alghoul, Malak Moones Abedi, Shabil Fathah Farook, Ibrahim Khalil Alabid, Mohammed Dalbah, Natasha Nasser, Samreen Fazal, Mariam Radhi Al-Talqani, Mohammed Mahmood Ali, Ebrahim Safaii, Wed Burhan Jameel Al-Shammari, Burhanuddin Murtaza Patanwala
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-05-01
Col·lecció:	Biomolecules
Matèries:	adenosine signaling CD39–CD73 axis adenosine receptors metabolic stress signaling tumor microenvironment immune modulation
Accés en línia:	https://www.mdpi.com/2218-273X/16/5/732
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