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Generation of Foxp3+CD25− Regulatory T-Cell Precursors Requires c-Rel and IκBNS

Next to the classical developmental route, in which first CD25 and subsequently Foxp3 are induced to generate thymic regulatory T (Treg) cells, an alternative route has been described. This alternative route is characterized by reciprocal induction of Foxp3 and CD25, with CD25 induction being requir...

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Hlavní autoři: Marc Schuster, Carlos Plaza-Sirvent, Alexander Visekruna, Jochen Huehn, Ingo Schmitz
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019-07-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/article/10.3389/fimmu.2019.01583/full
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