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Genetic variation in FOXP3 and ROR-γ genes in pediatric acute lymphocytic leukemia (ALL) patients: correlation with associated cytokines

Abstract Background FOXP3 and ROR-γ genes are master regulators of the Treg and Th17 differentiation, respectively. This work was planned to investigate the impact of FOXP3 (rs3761548C/A and rs3761549C/T) and ROR-γ (rs9017A/G & rs9826A/G) gene polymorphism on the vulnerability of pediatric Egyptians...

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Principais autores: Eman A. El-maadawy, Rania M. Bakry, Mohamed M. Moussa, Sobhy Hasab El-Naby, Roba M. Talaat
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer 2022-09-01
סדרה:Discover Oncology
נושאים:
Pediatric ALL
FOXP3
ROR-γ
SNPs
Cytokines
Treg/Th17 cells
גישה מקוונת:https://doi.org/10.1007/s12672-022-00549-3
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