Metabolic profiling and flux analysis of MEL-2 human embryonic stem cells during exponential growth at physiological and atmospheric oxygen concentrations.

As human embryonic stem cells (hESCs) steadily progress towards regenerative medicine applications there is an increasing emphasis on the development of bioreactor platforms that enable expansion of these cells to clinically relevant numbers. Surprisingly little is known about the metabolic requirem...

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Principais autores:	Jennifer Turner, Lake-Ee Quek, Drew Titmarsh, Jens O Krömer, Li-Pin Kao, Lars Nielsen, Ernst Wolvetang, Justin Cooper-White
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2014-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC4239018?pdf=render
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