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Metabolic profiling and flux analysis of MEL-2 human embryonic stem cells during exponential growth at physiological and atmospheric oxygen concentrations.

As human embryonic stem cells (hESCs) steadily progress towards regenerative medicine applications there is an increasing emphasis on the development of bioreactor platforms that enable expansion of these cells to clinically relevant numbers. Surprisingly little is known about the metabolic requirem...

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Bibliografische gegevens
Hoofdauteurs: Jennifer Turner, Lake-Ee Quek, Drew Titmarsh, Jens O Krömer, Li-Pin Kao, Lars Nielsen, Ernst Wolvetang, Justin Cooper-White
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2014-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC4239018?pdf=render
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