The prognostic impact of myeloid co-mutation burden in TP53-mutated AML/MDS after allogeneic stem cell transplantation: a multicenter retrospective analysis

Abstract TP53 mutations are associated with poor prognosis in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Allogeneic hematopoietic stem cell transplantation (allo-HSCT) offers a potential cure, but outcomes are suboptimal and risk stratification remains challenging. This multi-...

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Autori principali:	Yao Sun, Shanshan Qin, Lu Wang, Hai Yi, Li Ding, Bo Cai, Na Liu, Yuhang Li, Jiangwei Hu, Zhuoqing Qiao, Fei Li, Daihong Liu, Liping Dou, Liangding Hu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Springer 2026-03-01
Serie:	Annals of Hematology
Soggetti:	Acute myeloid leukemia Myelodysplastic syndromes TP53 mutation Allogeneic hematopoietic stem cell transplantation (allo-HSCT) Co-mutation
Accesso online:	https://doi.org/10.1007/s00277-026-06895-4
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