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Low-VAF TP53-Mutated AML Displays Distinct Biological Features in a Single-Center Cohort

<b>Background</b>: The International Consensus Classification (ICC) currently proposes an empirical variant allele frequency (VAF) threshold of 10% to define TP53-mutated acute myeloid leukemia (AML) and to distinguish oncogenic driver from concomitant mutations. However, the optimal cutoff remains...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Xiaoxuan Lu, Xiaohang Ma, Kainan Zhang, Shun Zhang, Fangfang Wei, Hao Jiang, Qian Jiang, Yingjun Chang, Xiaojun Huang, Xiaosu Zhao
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2026-01-01
Rangatū:Biomedicines
Ngā marau:
Urunga tuihono:https://www.mdpi.com/2227-9059/14/1/180
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