Differential Intrasplenic Migration of Dendritic Cell Subsets Tailors Adaptive Immunity

Evidence suggests that distinct splenic dendritic cell (DC) subsets activate either CD4+ or CD8+ T cells in vivo. This bias has been partially ascribed to differential antigen presentation; however, all DC subsets can activate both T cell lineages in vitro. Therefore, we tested whether the organizat...

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Principais autores:	Samuele Calabro, Dong Liu, Antonia Gallman, Manuela Sales L. Nascimento, Zizi Yu, Ting-ting Zhang, Pei Chen, Biyan Zhang, Lan Xu, Uthaman Gowthaman, Jayendra Kumar Krishnaswamy, Ann M. Haberman, Adam Williams, Stephanie C. Eisenbarth
格式:	Artigo
语言:	Inglês
出版:	Elsevier 2016-08-01
丛编:	Cell Reports
主题:	dendritic cell spleen T cell red blood cell alloimmunization CCR7
在线阅读:	http://www.sciencedirect.com/science/article/pii/S2211124716310221
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