Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin
Ivermectin is a gold standard anthelmintic drug that works by potently depressing neuronal activity and muscular contractility in arthropods and nematodes. At the molecular level, ivermectin activates inhibitory glutamate-gated chloride channels (GluClRs), which are found exclusively in invertebrate...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2012-05-01
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| coleção: | Frontiers in Molecular Neuroscience |
| Assuntos: | |
| Acesso em linha: | http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00060/full |
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