Pre-marking chromatin with H3K4 methylation is required for accurate zygotic genome activation and development

Abstract In vertebrate embryos, gene expression is first initiated at zygotic genome activation (ZGA). Maternally expressed transcription factors are essential for this process. However, it is unknown whether active chromatin modifications established in gametes are present in early embryos and cont...

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ग्रंथसूची विवरण

मुख्य लेखकों:	Meghana S. Oak, Marco Stock, Ana Janeva, Matthias Mezes, Antony M. Hynes-Allen, Tobias Straub, Ignasi Forné, Andreas Ettinger, Stephan Hamperl, Axel Imhof, Jelle van den Ameele, Antonio Scialdone, Eva Hörmanseder
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Nature Portfolio 2025-12-01
श्रृंखला:	Nature Communications
ऑनलाइन पहुंच:	https://doi.org/10.1038/s41467-025-67692-7
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