Pre-marking chromatin with H3K4 methylation is required for accurate zygotic genome activation and development

Abstract In vertebrate embryos, gene expression is first initiated at zygotic genome activation (ZGA). Maternally expressed transcription factors are essential for this process. However, it is unknown whether active chromatin modifications established in gametes are present in early embryos and cont...

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Главные авторы:	Meghana S. Oak, Marco Stock, Ana Janeva, Matthias Mezes, Antony M. Hynes-Allen, Tobias Straub, Ignasi Forné, Andreas Ettinger, Stephan Hamperl, Axel Imhof, Jelle van den Ameele, Antonio Scialdone, Eva Hörmanseder
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2025-12-01
Серии:	Nature Communications
Online-ссылка:	https://doi.org/10.1038/s41467-025-67692-7
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