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Targeting IL-6 by engineered Lactococcus lactis via surface-displayed affibody

Abstract Background Dysregulated production of interleukin (IL)-6 is implicated in the pathology of inflammatory bowel disease (IBD). Neutralization of IL-6 in the gut by safe probiotic bacteria may help alleviate intestinal inflammation. Here, we developed Lactococcus lactis with potent and selecti...

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Bibliografische gegevens
Hoofdauteurs: Abida Zahirović, Aleš Berlec
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2022-07-01
Reeks:Microbial Cell Factories
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Online toegang:https://doi.org/10.1186/s12934-022-01873-7
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