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Cannabidiol’s cytotoxicity in pancreatic cancer is induced via an upregulation of ceramide synthase 1 and ER stress

Abstract Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive malignancies with a median 5 year-survival rate of 12%. Cannabidiol (CBD) has been found to exhibit antineoplastic potential and may potentiate the anticancer effects of cytotoxic’s such as gemcitabine. CBD therapy h...

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Principais autores: Nagina Mangal, Vikash Reebye, Nagy Habib, Mikael H. Sodergren
格式: Artigo
語言:Inglês
出版: BMC 2024-05-01
叢編:Journal of Cannabis Research
主題:
在線閱讀:https://doi.org/10.1186/s42238-024-00227-x
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