Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases

Bacterial pathogens have evolved intricate mechanisms to evade the human immune system, including the production of immunomodulatory enzymes. Here, the authors establish the mechanisms of recognition and specific deglycosylation of IgG antibodies by the multi-modular enzymes EndoS and EndoS2

Détails bibliographiques

Auteurs principaux:	Beatriz Trastoy, Jonathan J. Du, Javier O. Cifuente, Lorena Rudolph, Mikel García-Alija, Erik H. Klontz, Daniel Deredge, Nazneen Sultana, Chau G. Huynh, Maria W. Flowers, Chao Li, Diego E. Sastre, Lai-Xi Wang, Francisco Corzana, Alvaro Mallagaray, Eric J. Sundberg, Marcelo E. Guerin
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2023-03-01
Collection:	Nature Communications
Accès en ligne:	https://doi.org/10.1038/s41467-023-37215-3
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!