Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases

Bacterial pathogens have evolved intricate mechanisms to evade the human immune system, including the production of immunomodulatory enzymes. Here, the authors establish the mechanisms of recognition and specific deglycosylation of IgG antibodies by the multi-modular enzymes EndoS and EndoS2

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Beatriz Trastoy, Jonathan J. Du, Javier O. Cifuente, Lorena Rudolph, Mikel García-Alija, Erik H. Klontz, Daniel Deredge, Nazneen Sultana, Chau G. Huynh, Maria W. Flowers, Chao Li, Diego E. Sastre, Lai-Xi Wang, Francisco Corzana, Alvaro Mallagaray, Eric J. Sundberg, Marcelo E. Guerin
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2023-03-01
Цуврал:	Nature Communications
Онлайн хандалт:	https://doi.org/10.1038/s41467-023-37215-3
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!