Comparing the intra-tumoral distribution of Gemcitabine, 5-Fluorouracil, and Capecitabine in a murine model of pancreatic ductal adenocarcinoma.

<h4>Purpose</h4>To develop a technique to compare the intra-tumoral distribution of the drug gemcitabine, its surrogate [18F]-fluoroarabinocytosine ([18F]-FAC) and related chemotherapeutics 5-FU and capecitabine in a pre-clinical model of pancreatic ductal adenocarcinoma (PDAC).<h4>Experimental desi...

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Hlavní autoři:	Louise M Fanchon, James Russell, Nagavarakishore Pillarsetty, Isabella O'Donoghue, Kishore Gangangari, Kenneth H Yu, John L Humm
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2020-01-01
Edice:	PLoS ONE
On-line přístup:	https://doi.org/10.1371/journal.pone.0231745
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