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Modulating the Mechanical Activation of TRPV4 at the Cell-Substrate Interface

Ion channels activated by mechanical inputs are important force sensing molecules in a wide array of mammalian cells and tissues. The transient receptor potential channel, TRPV4, is a polymodal, nonselective cation channel that can be activated by mechanical inputs but only if stimuli are applied di...

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Hauptverfasser: Setareh Sianati, Lioba Schroeter, Jessica Richardson, Andy Tay, Shireen R. Lamandé, Kate Poole
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021-01-01
Schriftenreihe:Frontiers in Bioengineering and Biotechnology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fbioe.2020.608951/full
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