From Genetics to Neuroinflammation: The Impact of ApoE4 on Microglial Function in Alzheimer’s Disease

Alzheimer’s disease (AD) is a debilitating neurodegenerative disorder marked by progressive cognitive decline and memory loss, impacting millions of people around the world. The apolipoprotein E4 (ApoE4) allele is the most prominent genetic risk factor for late-onset AD, dramatically increasing dise...

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Bibliografische Detailangaben

Hauptverfasser:	Daniela Dias, Camila Cabral Portugal, João Relvas, Renato Socodato
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-02-01
Schriftenreihe:	Cells
Schlagworte:	apolipoprotein E4 (ApoE4) microglia Alzheimer’s disease (AD) neuroinflammation amyloid-beta clearance neurodegeneration
Online-Zugang:	https://www.mdpi.com/2073-4409/14/4/243
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