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Nanotechnology for microglial targeting and inhibition of neuroinflammation underlying Alzheimer’s pathology

Abstract Background Alzheimer's disease (AD) is considered to have a multifactorial etiology. The hallmark of AD is progressive neurodegeneration, which is characterized by the deepening loss of memory and a high mortality rate in the elderly. The neurodegeneration in AD is believed to be exacerbate...

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Principais autores: Hoda M. Gebril, Aravind Aryasomayajula, Mariana Reis Nogueira de Lima, Kathryn E. Uhrich, Prabhas V. Moghe
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-01-01
Serier:Translational Neurodegeneration
Fag:
Amphiphilic nanoparticle
Microglia
Fibril amyloid beta
Alzheimer’s disease
Neuroinflammation
Scavenger receptor
Online adgang:https://doi.org/10.1186/s40035-023-00393-7
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