Pre-Clinical Evaluation of Tenofovir and Tenofovir Alafenamide for HIV-1 Pre-Exposure Prophylaxis in Foreskin Tissue

Background: HIV-1 pre-exposure prophylaxis (PrEP) has focused predominantly on protective efficacy in receptive sex, with limited research on the dosing requirements for insertive sex. We pre-clinically assessed the ex vivo pharmacokinetic–pharmacodynamic (PK–PD) profile of tenofovir (TFV) and tenof...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Laura Else, Sujan D. Penchala, Azure-Dee Pillay, Thabiso B. Seiphetlo, Limakatso Lebina, Christian Callebaut, Suks Minhas, Roland Morley, Tina Rashid, Neil Martinson, Julie Fox, Saye Khoo, Carolina Herrera
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-06-01
Serie:	Pharmaceutics
Soggetti:	HIV-1 foreskin pre-exposure prophylaxis
Accesso online:	https://www.mdpi.com/1999-4923/14/6/1285
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!