Brain atrophy and cholinergic denervation in progressive supranuclear palsy: an MRI and [18F]-FEOBV PET study

IntroductionProgressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by a wide spectrum of motor and cognitive impairments. Structural brain imaging biomarkers, such as the Magnetic Resonance Parkinsonism Index 2.0 (MRPI 2.0), are increasingly recognized as means of support...

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Principais autores:	Prabesh Kanel, Stiven Roytman, Giulia Carli, Robert Vangel, Jaimie Barr, Fotini Michalakis, Christopher Chauncey Spears, Peter J. H. Scott, Roger L. Albin, Nicolaas I. Bohnen
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2025-12-01
סדרה:	Frontiers in Neuroscience
נושאים:	progressive supranucelar palsy MRPI FEOBV PET midbrain
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1695541/full
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