PG-SCUnK: measuring pangenome graph representativeness using single-copy and universal K-mers

Abstract Background Pangenome graphs integrate multiple assemblies to represent non-redundant genetic diversity. However, current evaluations of pangenome graphs rely primarily on technical parameters (e.g., total length, number of nodes/edges, growth curves), which fail to assess how effectively th...

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主要な著者:	Tristan Cumer, Sotiria Milia, Alexander S. Leonard, Hubert Pausch
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-12-01
シリーズ:	BMC Bioinformatics
主題:	Pangenome graphs Single-copy k-mers Universal k-mers Graph representativeness Graph quality assessment
オンライン･アクセス:	https://doi.org/10.1186/s12859-025-06355-2
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