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High risk Langerhans cell histiocytosis in children: the role of salvage in improving the outcome. A single center experience

Abstract Background In pediatric multi-system high risk organs (RO +) Langerhans cell histiocytosis (LCH), failing 1st line treatment has the highest mortality. We aim to present the outcome of failure of 1st line whether due to disease progression (DP) at end of induction or reactivation (REA) afte...

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Principais autores: Mohamed Sedky M. Sedky, Asmaa Hamoda, Hala Taha, Iman Zaky, Omayma Hassanain, Alaa ElHaddad
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-06-01
Serier:Orphanet Journal of Rare Diseases
Fag:
2-CdA based regimen
High risk organs
LCH
Disease progression
Reactivation
Online adgang:https://doi.org/10.1186/s13023-024-03232-8
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