Structural and functional hepatic factors as prognostic indicators in children with Langerhans cell histiocytosis

Background and aimLangerhans cell histiocytosis (LCH) is a clonal myeloid neoplasm with variable outcomes; hepatic involvement is uniformly classified as high-risk. However, liver disease includes distinct structural and biochemical phenotypes with unclear prognostic significance. This study aimed t...

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Hlavní autoři:	Seham Hassan, Mohamed Sedky M Sedky, Asmaa Salama, Iman Zaky, Hany Girguis, Salma Abd ELKarim, Alaa ELHaddad
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-05-01
Edice:	Frontiers in Oncology
Témata:	hepatic dysfunction hepatomegaly Langerhans cell histiocytosis sclerosing cholangitis Z-score
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1813004/full
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