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Uncoupling time and space in the collinear regulation of Hox genes.

During development of the vertebrate body axis, Hox genes are transcribed sequentially, in both time and space, following their relative positions within their genomic clusters. Analyses of animal genomes support the idea that Hox gene clustering is essential for coordinating the various times of ge...

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Bibliografiske detaljer
Principais autores: Patrick Tschopp, Basile Tarchini, François Spitz, Jozsef Zakany, Denis Duboule
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2009-03-01
Serier:PLoS Genetics
Online adgang:http://europepmc.org/articles/PMC2642670?pdf=render
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