C5b-9 Membrane Attack Complex Formation and Extracellular Vesicle Shedding in Barrett’s Esophagus and Esophageal Adenocarcinoma

The early complement components have emerged as mediators of pro-oncogenic inflammation, classically inferred to cause terminal complement activation, but there are limited data on the activity of terminal complement in cancer. We previously reported elevated serum and tissue C9, the terminal comple...

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Hlavní autoři:	Cathryn M. Kolka, Julie Webster, Ailin Lepletier, Clay Winterford, Ian Brown, Renee S. Richards, Wioleta M. Zelek, Yilang Cao, Ramlah Khamis, Karthik B. Shanmugasundaram, Alain Wuethrich, Matt Trau, Sandra Brosda, Andrew Barbour, Alok K. Shah, Guy D. Eslick, Nicholas J. Clemons, B. Paul Morgan, Michelle M. Hill
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-03-01
Edice:	Frontiers in Immunology
Témata:	complement system activation extracellular vesicle (EV) microvesicle terminal complement component (SC5b-9) exosome
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.842023/full
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