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Candidalysins Are a New Family of Cytolytic Fungal Peptide Toxins

ABSTRACT Candidalysin is the first cytolytic peptide toxin identified in any human fungal pathogen. Candidalysin is secreted by Candida albicans and is critical for driving infection and host immune responses in several model systems. However, Candida infections are also caused by non-C. albicans sp...

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Principais autores: Jonathan P. Richardson, Rhys Brown, Nessim Kichik, Sejeong Lee, Emily Priest, Selene Mogavero, Corinne Maufrais, Don N. Wickramasinghe, Antzela Tsavou, Natalia K. Kotowicz, Olivia W. Hepworth, Ana Gallego-Cortés, Nicole O. Ponde, Jemima Ho, David L. Moyes, Duncan Wilson, Christophe D’Enfert, Bernhard Hube, Julian R. Naglik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2022-02-01
coleção:mBio
Assuntos:
Candida
candidalysin
fungus
peptide toxin
Acesso em linha:https://journals.asm.org/doi/10.1128/mbio.03510-21
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