Branched module-modified SN38 prodrug nanoassemblies for improved colorectal cancer therapy: Effectively balance efficacy and safety
The clinical utility of irinotecan is restricted by individual variability in carboxylesterase expression. Direct administration of its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN38), presents an appealing alternative due to its potent anti-tumor efficacy. However, the undesirable properti...
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| Principais autores: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Tsinghua University Press
2025-01-01
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| Serija: | Nano Research |
| Teme: | |
| Online dostop: | https://www.sciopen.com/article/10.26599/NR.2025.94907011 |
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