Immunogenicity of mucosal COVID-19 vaccine candidates based on the highly attenuated vesicular stomatitis virus vector (VSVMT) in golden syrian hamster

COVID-19 is caused by coronavirus SARS-CoV-2. Current systemic vaccines generally provide limited protection against viral replication and shedding within the airway. Recombinant VSV (rVSV) is an effective vector which inducing potent and comprehensive immunities. Currently, there are two clinical t...

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Principais autores:	Yong Ke, En Zhang, Jianming Guo, Xiaoxiao Zhang, Lei Wang, Duo Chen, Xinkui Fang, Jianwei Zhu, Feng Li, Tao Sun, Baohong Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2023-12-01
Series:	Acta Pharmaceutica Sinica B
Assuntos:	COVID-19 Vesicular stomatitis virus Matrix protein mutant Mucosal Vaccine Spike protein Variants of concerns
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2211383523003295
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