Immunogenicity of mucosal COVID-19 vaccine candidates based on the highly attenuated vesicular stomatitis virus vector (VSVMT) in golden syrian hamster

COVID-19 is caused by coronavirus SARS-CoV-2. Current systemic vaccines generally provide limited protection against viral replication and shedding within the airway. Recombinant VSV (rVSV) is an effective vector which inducing potent and comprehensive immunities. Currently, there are two clinical t...

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Главные авторы:	Yong Ke, En Zhang, Jianming Guo, Xiaoxiao Zhang, Lei Wang, Duo Chen, Xinkui Fang, Jianwei Zhu, Feng Li, Tao Sun, Baohong Zhang
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2023-12-01
Серии:	Acta Pharmaceutica Sinica B
Предметы:	COVID-19 Vesicular stomatitis virus Matrix protein mutant Mucosal Vaccine Spike protein Variants of concerns
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2211383523003295
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