Immunoinformatics-driven design of a multi-epitope vaccine targeting neonatal rotavirus with focus on outer capsid proteins VP4 and VP7 and non structural proteins NSP2 and NSP5

Abstract Rotaviral gastroenteritis remains a major global health concern, particularly for infants and young children under five years old. Prior to the introduction of the WHO-prequalified rotavirus vaccine, rotavirus (RV) was responsible for approximately 800,000 child deaths annually in developin...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Arijit Das Sharma, Jorge Samuel Leon Magdaleno, Himanshu Singh, Andrés Felipe Cuspoca Orduz, Luigi Cavallo, Mohit Chawla
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-04-01
coleção:	Scientific Reports
Assuntos:	Rotavirus Gastroenteritis Neonates Immunoinformatics Immune simulation Toll-like receptors (TLRs)
Acesso em linha:	https://doi.org/10.1038/s41598-025-95256-8
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!