Immunoinformatics-driven design of a multi-epitope vaccine targeting neonatal rotavirus with focus on outer capsid proteins VP4 and VP7 and non structural proteins NSP2 and NSP5

Abstract Rotaviral gastroenteritis remains a major global health concern, particularly for infants and young children under five years old. Prior to the introduction of the WHO-prequalified rotavirus vaccine, rotavirus (RV) was responsible for approximately 800,000 child deaths annually in developin...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Arijit Das Sharma, Jorge Samuel Leon Magdaleno, Himanshu Singh, Andrés Felipe Cuspoca Orduz, Luigi Cavallo, Mohit Chawla
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Nature Portfolio 2025-04-01
Σειρά:	Scientific Reports
Θέματα:	Rotavirus Gastroenteritis Neonates Immunoinformatics Immune simulation Toll-like receptors (TLRs)
Διαθέσιμο Online:	https://doi.org/10.1038/s41598-025-95256-8
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