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Carabin deficiency in B cells increases BCR‐TLR9 costimulation‐induced autoimmunity

Abstract The mechanisms behind flares of human autoimmune diseases in general, and of systemic lupus in particular, are poorly understood. The present scenario proposes that predisposing gene defects favour clinical flares under the influence of external stimuli. Here, we show that Carabin is low in...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jean‐Nicolas Schickel, Jean‐Louis Pasquali, Anne Soley, Anne‐Marie Knapp, Marion Decossas, Aurélie Kern, Jean‐Daniel Fauny, Luc Marcellin, Anne‐Sophie Korganow, Thierry Martin, Pauline Soulas‐Sprauel
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Springer Nature 2012-10-01
Rangatū:EMBO Molecular Medicine
Ngā marau:
Urunga tuihono:https://doi.org/10.1002/emmm.201201595
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