Carabin deficiency in B cells increases BCR‐TLR9 costimulation‐induced autoimmunity

Abstract The mechanisms behind flares of human autoimmune diseases in general, and of systemic lupus in particular, are poorly understood. The present scenario proposes that predisposing gene defects favour clinical flares under the influence of external stimuli. Here, we show that Carabin is low in...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jean‐Nicolas Schickel, Jean‐Louis Pasquali, Anne Soley, Anne‐Marie Knapp, Marion Decossas, Aurélie Kern, Jean‐Daniel Fauny, Luc Marcellin, Anne‐Sophie Korganow, Thierry Martin, Pauline Soulas‐Sprauel
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Springer Nature 2012-10-01
Цуврал:	EMBO Molecular Medicine
Нөхцлүүд:	autoimmunity B cells Carabin mouse models systemic lupus erythematosus
Онлайн хандалт:	https://doi.org/10.1002/emmm.201201595
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!