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Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors.

BACKGROUND: Stem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target cancer stem cells are thus of major importance for cancer therapy. Differentiation therapy by nucleoside drugs represents an attractiv...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Tanja Musch, Yuva Oz, Frank Lyko, Achim Breiling
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2010-01-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC2873290?pdf=render
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