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Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors.

BACKGROUND: Stem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target cancer stem cells are thus of major importance for cancer therapy. Differentiation therapy by nucleoside drugs represents an attractiv...

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Xehetasun bibliografikoak
Egile Nagusiak: Tanja Musch, Yuva Oz, Frank Lyko, Achim Breiling
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2010-01-01
Saila:PLoS ONE
Sarrera elektronikoa:http://europepmc.org/articles/PMC2873290?pdf=render
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