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System-Wide Associations between DNA-Methylation, Gene Expression, and Humoral Immune Response to Influenza Vaccination.

Failure to achieve a protected state after influenza vaccination is poorly understood but occurs commonly among aged populations experiencing greater immunosenescence. In order to better understand immune response in the elderly, we studied epigenetic and transcriptomic profiles and humoral immune r...

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Główni autorzy: Michael T Zimmermann, Ann L Oberg, Diane E Grill, Inna G Ovsyannikova, Iana H Haralambieva, Richard B Kennedy, Gregory A Poland
Format: Artigo
Język:Inglês
Wydane: Public Library of Science (PLoS) 2016-01-01
Seria:PLoS ONE
Dostęp online:http://europepmc.org/articles/PMC4816338?pdf=render
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