FERM domain containing protein 7 interacts with the Rho GDP dissociation inhibitor and specifically activates Rac1 signaling.

The FERM domain containing protein 7 gene (FRMD7) associated with the X-linked disorder idiopathic congenital nystagmus (ICN) is involved in the regulation of neurite elongation during neuronal development. Members of the Rho family of small G-proteins (Rho GTPases) are key regulators of the actin c...

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Autores principales:	Jiali Pu, Yanfang Mao, Xiaoguang Lei, Yaping Yan, Xiaoxiong Lu, Jun Tian, Xinzhen Yin, Guohua Zhao, Baorong Zhang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2013-01-01
Colección:	PLoS ONE
Acceso en línea:	http://europepmc.org/articles/PMC3742540?pdf=render
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