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Simultaneous fine mapping of closely linked epistatic quantitative trait loci using combined linkage disequilibrium and linkage with a general pedigree

<p>Abstract</p> <p>Causal mutations and their intra- and inter-locus interactions play a critical role in complex trait variation. It is often not easy to detect epistatic quantitative trait loci (QTL) due to complicated population structure requirements for detecting epistatic effects in linkage an...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Werf Julius, Lee Sang
Format: Artigo
Sprache:Alemão
Veröffentlicht: BMC 2008-05-01
Schriftenreihe:Genetics Selection Evolution
Schlagworte:
fine-mapping
multiple QTL
epistasis
dominance
reversible jump MCMC
Online-Zugang:http://www.gsejournal.org/content/40/3/265
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