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Simultaneous fine mapping of closely linked epistatic quantitative trait loci using combined linkage disequilibrium and linkage with a general pedigree

<p>Abstract</p> <p>Causal mutations and their intra- and inter-locus interactions play a critical role in complex trait variation. It is often not easy to detect epistatic quantitative trait loci (QTL) due to complicated population structure requirements for detecting epistatic effects in linkage an...

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Hlavní autoři: Werf Julius, Lee Sang
Médium: Artigo
Jazyk:Alemão
Vydáno: BMC 2008-05-01
Edice:Genetics Selection Evolution
Témata:
fine-mapping
multiple QTL
epistasis
dominance
reversible jump MCMC
On-line přístup:http://www.gsejournal.org/content/40/3/265
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