Anti-Tumor Efficacy of a Mesothelin-Based Nanovaccine in a KPC Orthotopic Mouse Model of Pancreatic Cancer

<b>Background/Objectives</b>: Immunotherapy has shown promising results in some cancers, but its efficacy remains limited in pancreatic ductal adenocarcinoma (PDAC). Vaccines in nanoparticle form (nanovaccines) can incorporate immunostimulating components to induce a potent immune response. As mesot...

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Principais autores:	Daniele P. Ferrari, Özmen Çobanoglu, Sana Sayedipour, Omar Luna, Sonia A. M. Ferkel, David Agorku, Yomkippur Perez, Luis J. Cruz, Fernando Albericio, François Trottein, Frauke Alves, Marietta Andrea Markus, Fernanda Ramos-Gomes
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2025-03-01
Series:	Vaccines
Assuntos:	pancreatic cancer immunotherapy CD8<sup>+</sup> T cells mesothelin nanoparticles
Acceso en liña:	https://www.mdpi.com/2076-393X/13/3/314
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