Anti-Tumor Efficacy of a Mesothelin-Based Nanovaccine in a KPC Orthotopic Mouse Model of Pancreatic Cancer

<b>Background/Objectives</b>: Immunotherapy has shown promising results in some cancers, but its efficacy remains limited in pancreatic ductal adenocarcinoma (PDAC). Vaccines in nanoparticle form (nanovaccines) can incorporate immunostimulating components to induce a potent immune response. As mesot...

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Principais autores:	Daniele P. Ferrari, Özmen Çobanoglu, Sana Sayedipour, Omar Luna, Sonia A. M. Ferkel, David Agorku, Yomkippur Perez, Luis J. Cruz, Fernando Albericio, François Trottein, Frauke Alves, Marietta Andrea Markus, Fernanda Ramos-Gomes
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2025-03-01
叢編:	Vaccines
主題:	pancreatic cancer immunotherapy CD8<sup>+</sup> T cells mesothelin nanoparticles
在線閱讀:	https://www.mdpi.com/2076-393X/13/3/314
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