atpE Mutation in Mycobacterium tuberculosis Not Always Predictive of Bedaquiline Treatment Failure

We report the emergence of an atpE mutation in a clinical Mycobacterium tuberculosis strain. Genotypic and phenotypic bedaquiline susceptibility testing displayed variable results over time and ultimately were not predictive of treatment outcome. This observation highlights the limits of current ge...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Laure Fournier Le Ray, Alexandra Aubry, Wladimir Sougakoff, Matthieu Revest, Jérôme Robert, Isabelle Bonnet, Nicolas Veziris, Florence Morel
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Centers for Disease Control and Prevention 2022-05-01
Цуврал:	Emerging Infectious Diseases
Нөхцлүүд:	tuberculosis atpE bedaquiline MDR TB XDR TB Rv0678
Онлайн хандалт:	https://wwwnc.cdc.gov/eid/article/28/5/21-2517_article
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!