Matrix stiffness-related extracellular matrix signatures and the DYNLL1 protein promote hepatocellular carcinoma progression through the Wnt/β-catenin pathway

Abstract Background In hepatocellular carcinoma (HCC) treatment, first-line targeted therapy in combination with immune checkpoint inhibitors (ICIs) has improved patient prognosis, but the 5-year survival rate is far from satisfactory. Studies have shown that the extracellular matrix (ECM) is an ess...

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Principais autores:	Yang Shen, Jiayu Chen, Zhuolin Zhou, Jingyu Wu, Xinyao Hu, Yangtao Xu, Jiayi Li, Ling Wang, Siyu Wang, Shuhong Yu, Ling Feng, Ximing Xu
格式:	Artigo
語言:	Inglês
出版:	BMC 2024-09-01
叢編:	BMC Cancer
主題:	Hepatocellular carcinoma Matrix stiffness Extracellular matrix proteins Prognostic model DYNLL1 Wnt/β-catenin pathway
在線閱讀:	https://doi.org/10.1186/s12885-024-12973-5
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