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Sargachromenol Purified from <i>Sargassum horneri</i> Inhibits Inflammatory Responses via Activation of Nrf2/HO-1 Signaling in LPS-Stimulated Macrophages

In this study, we isolated sargachromenol (SC) from <i>Sargassum horneri</i> and evaluated its anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. SC did not show cytotoxicity at all concentrations and effectively increased the cell viability by reducing the nitric...

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Principais autores: Eui-Jeong Han, Thilina U. Jayawardena, Jae-Hyuk Jang, Ilekuttige Priyan Shanura Fernando, Youngheun Jee, You-Jin Jeon, Dae-Sung Lee, Jeong-Min Lee, Mi-Jin Yim, Lei Wang, Hyun-Soo Kim, Ginnae Ahn
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-08-01
Serier:Marine Drugs
Fag:
<i>Sargassum horneri</i>
sargachromenol
anti-inflammatory effect
Nrf2/HO-1 signaling
RAW 264.7 macrophages
Online adgang:https://www.mdpi.com/1660-3397/19/9/497
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